Install via pip vs. regular download

What is the difference between running Anki after it’s been installed via pip and running a regular build that was downloaded from the website? Aside from the fact that following the pip instructions (Intro & Downloads - Anki Betas) will install Anki in a virtual environment?

I know these instructions are specifically for beta builds, but can’t regular stable builds also be installed with pip by setting aqt=version-number?

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