To summarize the past few comments: another user on Reddit suggested giving Again a red outline and giving other buttons a green outline, and perhaps increasing the distance between Again and other buttons, which is exactly what I have proposed before.
If we can’t satisfy everyone - such as people with OCD and colorblind people - but can satisfy >90% of all people, then this seems like the best solution. If we can’t satisfy everyone, this solution is still better than not doing anything at all.